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Drug Name | NSC319726 |
Trade Name | |
Synonyms | NSC-319726|NSC 319726 |
Drug Descriptions |
NSC319726 restores wild-type conformation to mutant Tp53, resulting in reactivation of Tp53 signaling in Tp53-mutant cells, and potentially leading to increased tumor cell death (PMID: 22624712, PMID: 26719703). |
DrugClasses | p53 Activator 11 |
CAS Registry Number | 71555-25-4 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
NSC319726 | NSC319726 | 5 | 0 |