Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | G-631 |
Trade Name | |
Synonyms | |
Drug Descriptions |
G-631 inhibits Tankyrase 1 and 2 (TNK1, TNK2), resulting in decreased Wnt/Beta-catenin pathway signaling, but has little anti-tumor activity and leads to intestinal toxicity (PMID: 26692561). |
DrugClasses | Tankyrase Inhibitor 11 |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
G-631 | G-631 | 1 | 0 |