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Drug Name | APTO-253 |
Trade Name | |
Synonyms | LOR-253|LT-253 |
Drug Descriptions |
APTO-253 is a small molecule that induces expression of KLF4 and CDKN1A, resulting in decreased tumor cell proliferation, cell-cycle arrest, and apoptosis, and has been shown to induce DNA damage (PMID: 26268924, PMID: 29626127, PMID: 29626126). |
DrugClasses | |
CAS Registry Number | 1422731-37-0 |
NCIT ID | C95724 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
APTO-253 | APTO-253 | 0 | 1 |