APTO-253
Drug Detail
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| Drug Name | APTO-253 |
| Trade Name | |
| Synonyms | LOR-253|LT-253 |
| Drug Descriptions |
APTO-253 is a small molecule that induces expression of KLF4 and CDKN1A, resulting in decreased tumor cell proliferation, cell-cycle arrest, and apoptosis, and has been shown to induce DNA damage (PMID: 26268924, PMID: 29626127, PMID: 29626126). |
| DrugClasses | |
| CAS Registry Number | 1422731-37-0 |
| NCIT ID | C95724 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| APTO-253 | APTO-253 | 0 | 1 |
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