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Drug Name | Trazimera |
Trade Name | |
Synonyms | PF-05280014 |
Drug Descriptions |
Trazimera (PF-05280014) is a biosimilar to the ERBB2 (HER2)-targeted monoclonal antibody Herceptin (trastuzumab), which binds to the extracellular domain of ERBB2 (HER2) and leads to decreased growth of ERBB2 (HER2)-over expressing tumor cells (PMID: 25001079, PMID: 25041377, PMID: 31798693). |
DrugClasses | HER2 (ERBB2) Antibody 76 |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Paclitaxel + Trazimera | Paclitaxel Trazimera | 0 | 1 |
Trazimera | Trazimera | 0 | 0 |