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Drug Name | BMS-986156 |
Trade Name | |
Synonyms | BMS986156|BMS 986156 |
Drug Descriptions |
BMS-986156 is an activating monoclonal antibody that binds to TNFRSF18 (GITR, CD357), which leads to the activation of effector T cells and a decrease in T-regulatory cells, subsequently resulting in antitumor activity (Journal of Clinical Oncology 35, no. 15_suppl (May 2017) 104-104, PMID: 31697308). |
DrugClasses | GITR Antibody 7 |
CAS Registry Number | NA |
NCIT ID | C132267 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
BMS-986156 | BMS-986156 | 0 | 1 |
BMS-986156 + Ipilimumab + Nivolumab | BMS-986156 Ipilimumab Nivolumab | 0 | 1 |
BMS-986156 + Nivolumab | BMS-986156 Nivolumab | 0 | 2 |