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Drug Name GDC-0917
Trade Name
Synonyms CUDC-427|RG7459
Drug Descriptions

GDC-0917 (CUDC-427) is a SMAC mimetic, which acts as an antagonist to Inhibitor of Apoptosis Protein (IAP) family proteins, resulting in decreased tumor growth (PMID: 24041744, PMID: 27076626).

DrugClasses SMAC Mimetic 8
CAS Registry Number 1446182-94-0
NCIT ID C103825

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Therapy Name Drugs Efficacy Evidence Clinical Trials
GDC-0917 GDC-0917 0 1


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