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Drug Name | GDC-0917 |
Trade Name | |
Synonyms | CUDC-427|RG7459 |
Drug Descriptions |
GDC-0917 (CUDC-427) is a SMAC mimetic, which acts as an antagonist to Inhibitor of Apoptosis Protein (IAP) family proteins, resulting in decreased tumor growth (PMID: 24041744, PMID: 27076626). |
DrugClasses | SMAC Mimetic 8 |
CAS Registry Number | 1446182-94-0 |
NCIT ID | C103825 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
GDC-0917 | GDC-0917 | 0 | 1 |