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Drug Name | AT13148 |
Trade Name | |
Synonyms | AT-13148|AT 13148 |
Drug Descriptions |
AT13148 is a small molecule ATP-competitive inhibitor of AGC kinases including AKT1, AKT2, AKT3, p70S6K (RPS6KB1), PKA (PRKACA), ROCK1, ROCK2, RSK1, and SGK3, which results in decreased growth of tumor cells (PMID: 22781553, PMID: 25840982, PMID: 32616501). |
DrugClasses | AKT Inhibitor (Pan) - ATP competitive 7 PKA Inhibitor 2 |
CAS Registry Number | 1056901-62-2 |
NCIT ID | C101786 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AT13148 | AT13148 | 3 | 0 |