Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | Narazaciclib |
Trade Name | |
Synonyms | 7X|ON-123300|ON 123300|ON123300 |
Drug Descriptions |
Narazaciclib (ON123300) inhibits CDK4 and ARK5 (NUAK1), resulting in decreased downstream signaling and increased tumor cell death (PMID: 24417566, PMID: 26873845). |
DrugClasses | CDK4 Inhibitor 17 |
CAS Registry Number | 1357470-29-1 |
NCIT ID | C179641 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Dexamethasone + Narazaciclib | Dexamethasone Narazaciclib | 0 | 1 |
Letrozole + Narazaciclib | Letrozole Narazaciclib | 0 | 1 |
Narazaciclib | Narazaciclib | 0 | 1 |