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Drug Name | Tavolimab |
Trade Name | |
Synonyms | MEDI0562|MEDI-0562|Tavolixizumab |
Drug Descriptions |
Tavolimab (MEDI0562) is an activating monoclonal antibody to TNFRSF4 (OX40, CD134), which mimics the binding of the ligand, TNFSF4 (OX40L, CD252), to stimulate proliferation of T-cells and enhance an anti-tumor response (Annals of Oncology, Volume 27, Issue suppl_6, 1 October 2016, 1052PD). |
DrugClasses | OX40 Antibody 14 |
CAS Registry Number | 1635395-25-3 |
NCIT ID | C120041 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Durvalumab + Tavolimab | Durvalumab Tavolimab | 0 | 1 |
Tavolimab | Tavolimab | 0 | 2 |
Tavolimab + Tremelimumab | Tavolimab Tremelimumab | 0 | 2 |