Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | CBL0137 |
Trade Name | |
Synonyms | CBL 0137|CBL-0137 |
Drug Descriptions |
CBL0137 is a curaxin compound that binds to and inhibits the facilitates chromatin transcription (FACT) complex, resulting in apoptosis in cancer cells (PMID: 25402820) and also disrupts DNA and histone interactions (PMID: 30926878, PMID: 32631516, PMID: 32202904). |
DrugClasses | |
CAS Registry Number | 1197996-80-7 |
NCIT ID | C107239 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CBL0137 | CBL0137 | 0 | 4 |
CBL0137 + Gemcitabine | CBL0137 Gemcitabine | 0 | 0 |
CBL0137 + Ipilimumab + Nivolumab | CBL0137 Ipilimumab Nivolumab | 0 | 1 |