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Drug Name | CFI-400945 |
Trade Name | |
Synonyms | |
Drug Descriptions |
CFI-400945 is a selective Polo-like kinase 4 (PLK4) inhibitor that inhibits cell division and induces apoptosis in tumor cells (PMID: 25043604, PMID: 31303643). |
DrugClasses | |
CAS Registry Number | 1338806-76-0 |
NCIT ID | C111990 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Azacitidine + CFI-400945 | Azacitidine CFI-400945 | 0 | 1 |
CFI-400945 | CFI-400945 | 1 | 4 |
CFI-400945 + Decitabine | CFI-400945 Decitabine | 0 | 1 |
CFI-400945 + Durvalumab | CFI-400945 Durvalumab | 0 | 1 |