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Drug Name XMT-1536
Trade Name
Synonyms XMT1536|XMT 1536|Upifitamab Rilsodotin|Anti-NaPi2b ADC XMT-1536
Drug Descriptions

XMT-1536 is an anti-type II sodium-dependent potassium transporter (NaPi2b) antibody in conjugation with cytotoxic auristatin molecules, which delivers auristatin to tumor cells over expressing NaPi2b and results in tumor cell death (Proceedings of AACR, Vol 57, Apr 2016, Abstract # 1194).

DrugClasses
CAS Registry Number NA
NCIT ID C147577

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + XMT-1536 Carboplatin XMT-1536 0 1
XMT-1536 XMT-1536 0 1


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