Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | XMT-1536 |
Trade Name | |
Synonyms | XMT1536|XMT 1536|Upifitamab Rilsodotin|Anti-NaPi2b ADC XMT-1536 |
Drug Descriptions |
XMT-1536 is an anti-type II sodium-dependent potassium transporter (NaPi2b) antibody in conjugation with cytotoxic auristatin molecules, which delivers auristatin to tumor cells over expressing NaPi2b and results in tumor cell death (Proceedings of AACR, Vol 57, Apr 2016, Abstract # 1194). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C147577 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Carboplatin + XMT-1536 | Carboplatin XMT-1536 | 0 | 1 |
XMT-1536 | XMT-1536 | 0 | 1 |