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Drug Name | AZD4635 |
Trade Name | |
Synonyms | AZD 4635|AZD-4635 |
Drug Descriptions |
AZD4635 binds to and inhibits the adenosine A2A (ADORA2A) receptor on immune cells, resulting in activation of an anti-tumor immune response by blocking binding of the immunosuppressive metabolite, adenosine (PMID: 29758241, PMID: 32727810). |
DrugClasses | Adenosine Targeting 23 |
CAS Registry Number | 1321514-06-0 |
NCIT ID | C148039 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AZD4635 | AZD4635 | 0 | 1 |
AZD4635 + Cabazitaxel + Durvalumab | AZD4635 Cabazitaxel Durvalumab | 0 | 1 |
AZD4635 + Durvalumab | AZD4635 Durvalumab | 0 | 3 |
AZD4635 + Oleclumab | AZD4635 Oleclumab | 0 | 2 |