AZD4635
Drug Detail
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| Drug Name | AZD4635 |
| Trade Name | |
| Synonyms | AZD 4635|AZD-4635 |
| Drug Descriptions |
AZD4635 binds to and inhibits the adenosine A2A (ADORA2A) receptor on immune cells, resulting in activation of an anti-tumor immune response by blocking binding of the immunosuppressive metabolite, adenosine (PMID: 29758241, PMID: 32727810). |
| DrugClasses | Adenosine Targeting 24 |
| CAS Registry Number | 1321514-06-0 |
| NCIT ID | C148039 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| AZD4635 | AZD4635 | 0 | 1 |
| AZD4635 + Cabazitaxel + Durvalumab | AZD4635 Cabazitaxel Durvalumab | 0 | 1 |
| AZD4635 + Durvalumab | AZD4635 Durvalumab | 0 | 3 |
| AZD4635 + Oleclumab | AZD4635 Oleclumab | 0 | 2 |
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