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Drug Name | JCAR014 |
Trade Name | |
Synonyms | |
Drug Descriptions |
JCAR014 is composed of autologous CD8 and CD4+ memory T-cells expressing a chimeric antigen receptor (CAR) comprised of a CD19 scFv-4-1BB-CD3zeta fusion protein and truncated EGFR, which may stimulate anti-tumor immunity (NCI Drug Dictionary). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C126639 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cyclophosphamide + Durvalumab + JCAR014 | Cyclophosphamide Durvalumab JCAR014 | 0 | 1 |
JCAR014 | JCAR014 | 0 | 0 |