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Drug Name | Pexmetinib |
Trade Name | |
Synonyms | ARRY-614 |
Drug Descriptions |
Pexmetinib (ARRY-614) inhibits Tie2, p38, and the BCR-ABL1 fusion, potentially leading to decreased cell proliferation and inhibition of tumor growth (PMID: 27287719, PMID: 25480830, PMID: 38750137). |
DrugClasses | BCR-ABL Inhibitor 32 |
CAS Registry Number | 945614-12-0 |
NCIT ID | C85481 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Ipilimumab + Pexmetinib | Ipilimumab Pexmetinib | 0 | 1 |
Nivolumab + Pexmetinib | Nivolumab Pexmetinib | 0 | 1 |
Pexmetinib | Pexmetinib | 0 | 0 |