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Drug Name | Debio 0617B |
Trade Name | |
Synonyms | |
Drug Descriptions |
Debio 0617B is a multi-kinase inhibitor of SRC, JAK, and ABL, the class III kinases, CSF1R, FLT3, KIT, and PDGFR, and the class V kinases, VEGFR 1/2/3, which may result in inhibition of Stat3 and Stat5 signaling, leading to inhibition of tumor cell growth and metastasis (PMID: 27439479, PMID: 28468777). |
DrugClasses | ABL Inhibitor (pan) 9 CSF1R Inhibitor 28 FLT3 Inhibitor 69 JAK Inhibitor (Pan) 9 KIT Inhibitor 57 PDGFR Inhibitor (Pan) 30 SRC Inhibitor 31 VEGFR Inhibitor (Pan) 36 |
CAS Registry Number | 1332329-27-7 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Debio 0617B | Debio 0617B | 0 | 0 |
Debio 0617B + Erlotinib | Debio 0617B Erlotinib | 0 | 0 |