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Drug Name | STA-8666 |
Trade Name | |
Synonyms | PEN-866|PEN866|STA-12-8666 |
Drug Descriptions |
STA-8666 is a molecule that targets active HSP90 and is linked to the active metabolite of Camptosar (irinotecan), SN38, which may result in antitumor activity including tumor stabilization and regression (PMID: 27267850, PMID: 27608846, PMID: 28453558). |
DrugClasses | HSP90 Inhibitor 35 |
CAS Registry Number | 1472614-83-7 |
NCIT ID | C151953 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Carboplatin + STA-8666 | Carboplatin STA-8666 | 0 | 0 |
STA-8666 | STA-8666 | 0 | 1 |
STA-8666 + Temozolomide + Vincristine Sulfate | STA-8666 Temozolomide Vincristine Sulfate | 0 | 1 |