AZD5153
Drug Detail
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| Drug Name | AZD5153 |
| Trade Name | |
| Synonyms | AZD-5153 |
| Drug Descriptions |
AZD5153 is a selective BET inhibitor that binds to BRD4 bivalently, resulting in enhanced anti-tumor activity (PMID: 27573426, PMID: 31392631). |
| DrugClasses | BRD4 Inhibitor 11 |
| CAS Registry Number | 1869912-39-9 |
| NCIT ID | C151943 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| AZD5153 | AZD5153 | 1 | 1 |
| AZD5153 + Durvalumab | AZD5153 Durvalumab | 0 | 0 |
| AZD5153 + Durvalumab + Selumetinib | AZD5153 Durvalumab Selumetinib | 0 | 1 |
| AZD5153 + Olaparib | AZD5153 Olaparib | 0 | 0 |
| AZD5153 + Selumetinib | AZD5153 Selumetinib | 0 | 1 |
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