Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | E7107 |
Trade Name | |
Synonyms | E 7107|E-7107 |
Drug Descriptions |
E7107 is a derivative of Pladienolide D, which inhibits assembly of the spliceosome specifically by binding to SF3B1, thereby inhibiting splicing of pre-mRNA and cell-cycle progression (PMID: 27622333, PMID: 31558432). |
DrugClasses | |
CAS Registry Number | 630100-90-2 |
NCIT ID | C69005 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
E7107 | E7107 | 0 | 0 |
E7107 + GSK3203591 | E7107 GSK3203591 | 0 | 0 |
E7107 + GSK3203591 + MS023 | E7107 GSK3203591 MS023 | 0 | 0 |
E7107 + MS023 | E7107 MS023 | 0 | 0 |