E7107
Drug Detail
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| Drug Name | E7107 |
| Trade Name | |
| Synonyms | E 7107|E-7107 |
| Drug Descriptions |
E7107 is a derivative of Pladienolide D, which inhibits assembly of the spliceosome specifically by binding to SF3B1, thereby inhibiting splicing of pre-mRNA and cell-cycle progression (PMID: 27622333, PMID: 31558432). |
| DrugClasses | |
| CAS Registry Number | 630100-90-2 |
| NCIT ID | C69005 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| E7107 | E7107 | 0 | 0 |
| E7107 + GSK3203591 | E7107 GSK3203591 | 0 | 0 |
| E7107 + GSK3203591 + MS023 | E7107 GSK3203591 MS023 | 0 | 0 |
| E7107 + MS023 | E7107 MS023 | 0 | 0 |
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