NS1
Drug Detail
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| Drug Name | NS1 |
| Trade Name | |
| Synonyms | |
| Drug Descriptions |
NS1 is a synthetic monobody that binds to GTP and GDP states of HRAS and KRAS, thereby inhibiting RAS dimerization and subsequent RAF activity, which may result in inhibition of cell transformation (PMID: 27820802, PMID: 29072601). |
| DrugClasses | HRAS Inhibitor 1 KRAS Inhibitor 30 |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| NS1 | NS1 | 4 | 0 |
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