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Drug Name | NS1 |
Trade Name | |
Synonyms | |
Drug Descriptions |
NS1 is a synthetic monobody that binds to GTP and GDP states of HRAS and KRAS, thereby inhibiting RAS dimerization and subsequent RAF activity, which may result in inhibition of cell transformation (PMID: 27820802, PMID: 29072601). |
DrugClasses | HRAS Inhibitor 1 KRAS Inhibitor 18 |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
NS1 | NS1 | 4 | 0 |