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Drug Name | INCB059872 |
Trade Name | |
Synonyms | |
Drug Descriptions |
INCB059872 is a specific inhibitor of lysine specific demethylase 1 (KDM1A, LSD1) that increases tumor-suppressor gene expression through enhancing Histone H3 methylation, leading to anti-tumor effects (Cancer Res 2016;76(14 Suppl):Abstract nr 4704, PMID: 32422235). |
DrugClasses | KDM1A Inhibitor 15 |
CAS Registry Number | NA |
NCIT ID | C126421 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
INCB054329 + INCB059872 | INCB054329 INCB059872 | 0 | 0 |
INCB059872 | INCB059872 | 0 | 2 |