Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | BAY1436032 |
Trade Name | |
Synonyms | BAY-1436032|BAY 1436032 |
Drug Descriptions |
BAY1436032 inhibits mutant IDH1, resulting in decreased levels of (R)-2-hydroxyglutarate (R-2HG) and leading to reduced proliferation and increased differentiation of IDH1-mutant tumor cells (PMID: 28232670, PMID: 32733012). |
DrugClasses | IDH1 Inhibitor 8 |
CAS Registry Number | 1803274-65-8 |
NCIT ID | C131690 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
BAY1436032 | BAY1436032 | 8 | 2 |