Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name CFI-402257
Trade Name
Synonyms
Drug Descriptions

CFI-402257 selectively inhibits TTK (MPS1), resulting in chromosomal segregation errors, and potentially leading to decreased tumor cell growth (PMID: 28270606, PMID: 29378962).

DrugClasses MPS1 Inhibitor 27
CAS Registry Number 1610759-22-2
NCIT ID C128288

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
CFI-402257 CFI-402257 0 2
CFI-402257 + Fulvestrant CFI-402257 Fulvestrant 0 1
CFI-402257 + Paclitaxel CFI-402257 Paclitaxel 0 1
CFI-402257 + unspecified PD-1 antibody CFI-402257 unspecified PD-1 antibody 0 0


Additional content available in CKB BOOST