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Drug Name | CFI-402257 |
Trade Name | |
Synonyms | |
Drug Descriptions |
CFI-402257 selectively inhibits TTK (MPS1), resulting in chromosomal segregation errors, and potentially leading to decreased tumor cell growth (PMID: 28270606, PMID: 29378962). |
DrugClasses | MPS1 Inhibitor 27 |
CAS Registry Number | 1610759-22-2 |
NCIT ID | C128288 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CFI-402257 | CFI-402257 | 0 | 2 |
CFI-402257 + Fulvestrant | CFI-402257 Fulvestrant | 0 | 1 |
CFI-402257 + Paclitaxel | CFI-402257 Paclitaxel | 0 | 1 |
CFI-402257 + unspecified PD-1 antibody | CFI-402257 unspecified PD-1 antibody | 0 | 0 |