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Drug Name Selitrectinib
Trade Name
Synonyms LOXO-195|BAY 2731954
Drug Descriptions

Selitrectinib (LOXO-195) is an inhibitor of NTRK1, NTRK2, and NTRK3, which may result in inhibition of tumor growth and tumor regression (PMID: 28578312).

DrugClasses Trk Receptor Inhibitor (Pan) 32
CAS Registry Number 2097002-61-2
NCIT ID C138160

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Crizotinib + Selitrectinib Crizotinib Selitrectinib 0 0
Dabrafenib + Selitrectinib + Trametinib Dabrafenib Selitrectinib Trametinib 0 0
Selitrectinib Selitrectinib 0 1
Selitrectinib + Trametinib Selitrectinib Trametinib 0 0


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