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Drug Name | Selitrectinib |
Trade Name | |
Synonyms | LOXO-195|BAY 2731954 |
Drug Descriptions |
Selitrectinib (LOXO-195) is an inhibitor of NTRK1, NTRK2, and NTRK3, which may result in inhibition of tumor growth and tumor regression (PMID: 28578312). |
DrugClasses | Trk Receptor Inhibitor (Pan) 32 |
CAS Registry Number | 2097002-61-2 |
NCIT ID | C138160 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Crizotinib + Selitrectinib | Crizotinib Selitrectinib | 0 | 0 |
Dabrafenib + Selitrectinib + Trametinib | Dabrafenib Selitrectinib Trametinib | 0 | 0 |
Selitrectinib | Selitrectinib | 0 | 1 |
Selitrectinib + Trametinib | Selitrectinib Trametinib | 0 | 0 |