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Drug Name | BGB659 |
Trade Name | |
Synonyms | ML 786 |
Drug Descriptions |
BGB659 is a pan-RAF inhibitor that results in inhibition of MEK/ERK signaling generated by either RAF dimers or RAF monomers and thus, prevents cell proliferation (PMID: 26343582). |
DrugClasses | RAF Inhibitor (Pan) 28 |
CAS Registry Number | 1237536-18-3 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
BGB659 | BGB659 | 2 | 0 |
BGB659 + Cetuximab | BGB659 Cetuximab | 2 | 0 |