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Drug Name | Oportuzumab monatox |
Trade Name | |
Synonyms | VB4-845|Vicinium|Proxinium |
Drug Descriptions |
Oportuzumab monatox (VB4-845) comprises an EpCAM-targeted monoclonal antibody fragment linked to Pseudomonas endotoxin A, which may result in decreased protein synthesis in EpCAM-expressing tumor cells (PMID: 31847708). |
DrugClasses | |
CAS Registry Number | 945228-48-8 |
NCIT ID | C61307 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Durvalumab + Oportuzumab monatox | Durvalumab Oportuzumab monatox | 0 | 1 |
Oportuzumab monatox | Oportuzumab monatox | 0 | 1 |