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Drug Name | A-485 |
Trade Name | |
Synonyms | A385 |
Drug Descriptions |
A-485 is a selective histone acetyltransferase inhibitor of EP300 and CREBBP, which induces cellular senescence, and may result in decreased cell proliferation and inhibition of tumor growth (PMID: 28953875, PMID: 30266801, PMID: 32366905). |
DrugClasses | CBP/p300 inhibitor 13 |
CAS Registry Number | 1889279-16-6 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
A-485 | A-485 | 0 | 0 |
A-485 + Alisertib | A-485 Alisertib | 0 | 0 |
A-485 + JQ1 | A-485 JQ1 | 0 | 0 |