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Drug Name | TAK-243 |
Trade Name | |
Synonyms | MLN7243 |
Drug Descriptions |
TAK-243 (MLN7243) is an inhibitor that selectively targets the ubiquitin activating enzyme, UBA1, which may result in inhibition of ubiquitination related processes such as cell cycle progression, apoptotic regulation, and DNA damage response (Mol Cancer Ther 2015;14(12 Suppl 2):Abstract nr A164, PMID: 28711351). |
DrugClasses | |
CAS Registry Number | 1450833-55-2 |
NCIT ID | C113788 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Carboplatin + TAK-243 | Carboplatin TAK-243 | 0 | 0 |
Docetaxel + TAK-243 | Docetaxel TAK-243 | 0 | 0 |
Radiotherapy + TAK-243 | Radiotherapy TAK-243 | 0 | 0 |
TAK-243 | TAK-243 | 0 | 2 |