Cusatuzumab
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| Drug Name | Cusatuzumab |
| Trade Name | |
| Synonyms | ARGX-110|JNJ-74494550 |
| Drug Descriptions |
Cusatuzumab (ARGX-110) is a monoclonal antibody that targets CD70, resulting in inhibition of CD70-CD27-mediated signaling and enhanced immune response against CD70-expressing tumor cells (PMID: 28765328, PMID: 24492296, PMID: 32601337). |
| DrugClasses | CD70 Antibody 6 |
| CAS Registry Number | 1864871-20-4 |
| NCIT ID | C106116 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Azacitidine + Cusatuzumab | Azacitidine Cusatuzumab | 0 | 3 |
| Azacitidine + Cusatuzumab + Venetoclax | Azacitidine Cusatuzumab Venetoclax | 0 | 2 |
| Cusatuzumab | Cusatuzumab | 0 | 0 |
| Cusatuzumab + Decitabine | Cusatuzumab Decitabine | 0 | 0 |
| Cusatuzumab + Venetoclax | Cusatuzumab Venetoclax | 0 | 1 |
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