S44563
Drug Detail
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| Drug Name | S44563 |
| Trade Name | |
| Synonyms | |
| Drug Descriptions |
S44563 binds to BCL-2 and BCL-XL and inhibits their interaction with BH3, which potentially results in increased tumor cell apoptosis and decreased tumor growth (PMID: 24454684, PMID: 25232677). |
| DrugClasses | BCL-XL inhibitor 14 BCL2 inhibitor 29 |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Fotemustine + S44563 | Fotemustine S44563 | 0 | 0 |
| S44563 | S44563 | 0 | 0 |
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