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| Drug Name | LY3381916 |
| Trade Name | |
| Synonyms | LY-3381916|LY 3381916 |
| Drug Descriptions |
LY3381916 binds to and inhibits indoleamine 2,3-dioxygenase 1 (IDO1), resulting in decreased conversion of tryptophan to kynurenine and potentially leading to increased activation of immune response against tumor cells (NCI Thesaurus). |
| DrugClasses | IDO1 Inhibitor 13 |
| CAS Registry Number | NA |
| NCIT ID | C143068 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| LY3300054 + LY3381916 | LY3300054 LY3381916 | 0 | 1 |
| LY3381916 | LY3381916 | 0 | 1 |