Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | LY3381916 |
Trade Name | |
Synonyms | LY-3381916|LY 3381916 |
Drug Descriptions |
LY3381916 binds to and inhibits indoleamine 2,3-dioxygenase 1 (IDO1), resulting in decreased conversion of tryptophan to kynurenine and potentially leading to increased activation of immune response against tumor cells (NCI Thesaurus). |
DrugClasses | IDO1 Inhibitor 12 |
CAS Registry Number | NA |
NCIT ID | C143068 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
LY3300054 + LY3381916 | LY3300054 LY3381916 | 0 | 1 |
LY3381916 | LY3381916 | 0 | 1 |