APG-1387
Drug Detail
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| Drug Name | APG-1387 |
| Trade Name | |
| Synonyms | APG1387|APG 1387|SM-1387 |
| Drug Descriptions |
APG-1387 is a SMAC mimetic, which antagonizes Inhibitor of Apoptosis (IAP) family proteins, potentially resulting in apoptosis of tumor cells and inhibition of tumor growth (PMID: 27424523, PMID: 30459627). |
| DrugClasses | SMAC Mimetic 8 |
| CAS Registry Number | 1570231-89-8 |
| NCIT ID | C162535 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| APG-1387 | APG-1387 | 0 | 1 |
| APG-1387 + Toripalimab-tpzi | APG-1387 Toripalimab-tpzi | 0 | 0 |
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