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Drug Name | CEP-11981 |
Trade Name | |
Synonyms | ESK981|CEP11981|CEP 11981 |
Drug Descriptions |
CEP-11981 is a multikinase inhibitor that targets VEGFR1-3 and TIE2, which may inhibit tumor angiogenesis and lead to tumor growth inhibition (PMID: 24982343, PMID: 25152243). |
DrugClasses | TIE2 Inhibitor 3 VEGFR Inhibitor (Pan) 36 |
CAS Registry Number | 856691-93-5 |
NCIT ID | C82379 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CEP-11981 | CEP-11981 | 0 | 3 |
CEP-11981 + Nivolumab | CEP-11981 Nivolumab | 0 | 2 |