GSK864
Drug Detail
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| Drug Name | GSK864 |
| Trade Name | |
| Synonyms | GSK 864|GSK-864 |
| Drug Descriptions |
GSK864 inhibits mutant IDH1, with additional activity against mutant IDH2, resulting in decreased production of 2HG and potentially leading to decreased growth of IDH-mutant tumors (PMID: 26436839, PMID: 28564604, PMID: 28986582, PMID: 30755816). |
| DrugClasses | IDH Inhibitor (Pan) 3 |
| CAS Registry Number | 1816331-66-4 |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| GSK864 | GSK864 | 2 | 0 |
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