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Drug Name | Naratuximab emtansine |
Trade Name | |
Synonyms | IMGN 529|Debio 156|IMGN529 |
Drug Descriptions |
Naratuximab emtansine (IMGN529) is an antibody-drug conjugate consisting of a humanized anti-CD37 monoclonal antibody linked to the anti-mitotic agent, maytansinoid DM1, thereby inducing cell death of B-cells expressing CD37 (PMID: 29453628, PMID: 28753442). |
DrugClasses | CD37 Antibody 8 |
CAS Registry Number | 1607824-64-5 |
NCIT ID | C100101 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Naratuximab emtansine | Naratuximab emtansine | 0 | 0 |
Naratuximab emtansine + Rituximab | Naratuximab emtansine Rituximab | 0 | 1 |