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Drug Name | FF-10101 |
Trade Name | |
Synonyms | FF-10101-01|FF10101|FF 10101 |
Drug Descriptions |
FF-10101 is a second generation and irreversible inhibitor of Flt3, including the internal tandem duplication (FLT3-ITD) and known resistance mutations (D835Y, Y842C, Y842H, or F691L) and also inhibits Kit and Csf1r (Fms) (PMID: 29187377, PMID: 32722298) |
DrugClasses | CSF1R Inhibitor 28 FLT3 Inhibitor 69 KIT Inhibitor 57 |
CAS Registry Number | 1472797-69-5 |
NCIT ID | C137988 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
FF-10101 | FF-10101 | 50 | 1 |
FF-10101 + Trametinib | FF-10101 Trametinib | 2 | 0 |