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| Drug Name | Flotetuzumab |
| Trade Name | |
| Synonyms | MGD006|S80880 |
| Drug Descriptions |
Flotetuzumab (MGD006) is a humanized bispecific antibody that targets both CD123 (IL32A) and CD23, which may lead to anti-leukemic activity (Blood 2017 130(Suppl 1):637, PMID: 32493790, PMID: 32929488). |
| DrugClasses | CD123 (IL3RA) Antibody 14 |
| CAS Registry Number | 1664355-28-5 |
| NCIT ID | C117238 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Acetaminophen + Dexamethasone + Diphenhydramine + Flotetuzumab + Ranitidine | Acetaminophen Dexamethasone Diphenhydramine Flotetuzumab Ranitidine | 0 | 1 |
| Cytarabine + Flotetuzumab | Cytarabine Flotetuzumab | 0 | 1 |
| Dexamethasone + Diphenhydramine + Flotetuzumab + Ibuprofen + Ranitidine | Dexamethasone Diphenhydramine Flotetuzumab Ibuprofen Ranitidine | 0 | 1 |
| Flotetuzumab | Flotetuzumab | 0 | 4 |