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Drug Name CC-90002
Trade Name
Synonyms CC90002|CC 90002
Drug Descriptions

CC-90002 is monoclonal antibody against CD47 that binds to and blocks CD47 downstream signaling and subsequent activation of the SIRPa receptor on macrophages, leading to phagocytosis of tumor cells (PMID: 28286286) and may also stimulate cytotoxic T-cells (PMID: 29873856).

DrugClasses CD47 Antibody 31 Immune Checkpoint Inhibitor 149
CAS Registry Number NA
NCIT ID C121211

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Therapy Name Drugs Efficacy Evidence Clinical Trials
CC-90002 CC-90002 0 2
CC-90002 + Rituximab CC-90002 Rituximab 0 1


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