CC-90002
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| Drug Name | CC-90002 |
| Trade Name | |
| Synonyms | CC90002|CC 90002 |
| Drug Descriptions |
CC-90002 is monoclonal antibody against CD47 that binds to and blocks CD47 downstream signaling and subsequent activation of the SIRPa receptor on macrophages, leading to phagocytosis of tumor cells (PMID: 28286286) and may also stimulate cytotoxic T-cells (PMID: 29873856). |
| DrugClasses | CD47 Antibody 31 Immune Checkpoint Inhibitor 150 |
| CAS Registry Number | NA |
| NCIT ID | C121211 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CC-90002 | CC-90002 | 0 | 2 |
| CC-90002 + Rituximab | CC-90002 Rituximab | 0 | 1 |
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