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Drug Name NI-1801
Trade Name
Synonyms NI 1801|NI1801
Drug Descriptions

NI-1801 is a bispecific antibody to CD47 and mesothelin, designed to target tumor cells expressing mesothelin and block CD47 downstream signaling and subsequent activation of the SIRPa receptor on macrophages, leading to phagocytosis of tumor cells (PMID: 28286286) may also stimulate cytotoxic T-cells (PMID: 29873856).

DrugClasses CD47 Antibody 31 Immune Checkpoint Inhibitor 149 MSLN Antibody 12
CAS Registry Number NA
NCIT ID C188247

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Therapy Name Drugs Efficacy Evidence Clinical Trials
NI-1801 NI-1801 0 1


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