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Drug Name | ADCT-601 |
Trade Name | |
Synonyms | ADCT601|ADCT 601|BGB 601|BGB601|BGB-601 |
Drug Descriptions |
ADCT-601 (BGB 601) is an antibody-drug conjugate (ADC) comprising an antibody targeting AXL linked to PL1601, which delivers the cytotoxic agent SG3199 to AXL-expressing tumor cells, potentially leading to decreased tumor growth (Cancer Res July 1 2018 (78) (13 Supplement) 2792A). |
DrugClasses | AXL Antibody 5 |
CAS Registry Number | NA |
NCIT ID | C160890 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ADCT-601 | ADCT-601 | 0 | 2 |
ADCT-601 + Gemcitabine | ADCT-601 Gemcitabine | 0 | 1 |
ADCT-601 + Olaparib | ADCT-601 Olaparib | 0 | 0 |