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Drug Name | BMS-986416 |
Trade Name | |
Synonyms | AVID200|AVID 200|AVID-200|BMS986416|BMS 986416 |
Drug Descriptions |
BMS-986416 (AVID200) is a TGF-beta receptor-based TGF-beta trap, which neutralizes TGF-beta1 and TGF-beta3 without interfering with TGF-beta2, resulting in decreased downstream signaling and potentially leading to increased recruitment and activation of anti-tumor T cells (Cancer Res July 1 2017 (77) (13 Supplement) 4688). |
DrugClasses | |
CAS Registry Number | 2269485-28-9 |
NCIT ID | C159817 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
BMS-986416 | BMS-986416 | 0 | 3 |
BMS-986416 + Nivolumab | BMS-986416 Nivolumab | 0 | 1 |