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Drug Name | anti-KRAS G12D mTCR cells |
Trade Name | |
Synonyms | |
Drug Descriptions |
Anti-KRAS G12D murine T-cell receptor (mTCR) cells are peripheral blood lymphocytes that have been transduced with a murine T-cell receptor that recognizes KRAS G12D, which may result in decreased growth of tumors harboring KRAS G12D (PMID: 26701267). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C156889 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Aldesleukin + anti-KRAS G12D mTCR cells + Cyclophosphamide + Fludarabine | Aldesleukin Cyclophosphamide Fludarabine anti-KRAS G12D mTCR cells | 0 | 1 |
anti-KRAS G12D mTCR cells | anti-KRAS G12D mTCR cells | 0 | 0 |