Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name Iruplinalkib
Trade Name
Synonyms WX0593|WX 0593|FL 006|FL-006|FL006|WX-0593
Drug Descriptions

Iruplinalkib (WX-0593) inhibits ALK and ROS1, with additional activity against EGFR mutations, which may lead to decreased tumor growth (PMID: 35087031; Cancer Res 2018;78(13 Suppl):Abstract nr 4794).

DrugClasses ALK Inhibitor 32 EGFR Inhibitor (Pan) 62 ROS1 Inhibitor 20
CAS Registry Number 1854943-32-0
NCIT ID C154279

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Iruplinalkib Iruplinalkib 21 0
Iruplinalkib + Panitumumab Iruplinalkib Panitumumab 0 0
Iruplinalkib + QL1203 Iruplinalkib QL1203 0 0


Additional content available in CKB BOOST