Anti-MAGE-A3-DP4 TCR T-cells
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| Drug Name | Anti-MAGE-A3-DP4 TCR T-cells |
| Trade Name | |
| Synonyms | Anti-MAGE-A3-DP4 TCR PBL |
| Drug Descriptions |
Anti-MAGE-A3-DP4 TCR T-cells are patient-derived T-lymphocytes that are modified to express a T-cell receptor that recognizes human melanoma antigen 3 (MAGEA3), which may result in increased killing of MAGE-A3-expressing tumor cells (PMID: 27163739). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Aldesleukin + Anti-MAGE-A3-DP4 TCR T-cells + Cyclophosphamide + Fludarabine | Aldesleukin Anti-MAGE-A3-DP4 TCR T-cells Cyclophosphamide Fludarabine | 0 | 1 |
| Anti-MAGE-A3-DP4 TCR T-cells | Anti-MAGE-A3-DP4 TCR T-cells | 0 | 0 |
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