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Drug Name | CC-95251 |
Trade Name | |
Synonyms | CC95251|CC 95251 |
Drug Descriptions |
CC-95251 is a monoclonal antibody directed against signal-regulatory protein alpha (SIRPA), which interferes with SIRPA-CD47 interaction, potentially resulting in increased immune response, leading to anti-tumor activity (Blood (2021) 138 (Supplement 1): 2493). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C157501 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Azacitidine + CC-95251 | Azacitidine CC-95251 | 0 | 1 |
CC-95251 | CC-95251 | 0 | 2 |
CC-95251 + Cetuximab | CC-95251 Cetuximab | 0 | 1 |
CC-95251 + Rituximab | CC-95251 Rituximab | 0 | 0 |