hu14.18-IL2
Drug Detail
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| Drug Name | hu14.18-IL2 |
| Trade Name | |
| Synonyms | Lorukafusp alfa|EMD-273063|EMD 273063|APN301|APN-301|APN 301 |
| Drug Descriptions |
Hu14.18-IL2 (Lorukafusp alfa) is a fusion protein comprised of a monoclonal antibody targeting the GD2 disialoganglioside linked to interleukin-2, which may inhibit growth of and induce an immune response against GD2-expressing tumors (PMID: 22844125, PMID: 20921469, PMID: 30073390). |
| DrugClasses | |
| CAS Registry Number | 2131168-99-3 |
| NCIT ID | C162537 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| hu14.18-IL2 | hu14.18-IL2 | 0 | 2 |
| hu14.18-IL2 + Ipilimumab + Nivolumab | Ipilimumab Nivolumab hu14.18-IL2 | 0 | 1 |
| hu14.18-IL2 + Nivolumab | Nivolumab hu14.18-IL2 | 0 | 1 |
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