Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name ARV-110
Trade Name
Synonyms ARV110|ARV 110|Bavdegalutamide
Drug Descriptions

ARV-110 is bifunctional molecule that targets androgen receptor (AR) for proteolytic degradation resulting in reduced target gene expression, potentially leading to decreased tumor growth inhibition and apoptosis (Journal of Clinical Oncology 37, no. 7_suppl (March 1 2019) 259-259, PMID: 32503798).

DrugClasses Hormone - Anti-androgens 54
CAS Registry Number NA
NCIT ID C160788

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Abiraterone + ARV-110 ARV-110 Abiraterone 0 1
ARV-110 ARV-110 0 1


Additional content available in CKB BOOST