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Drug Name | ARV-110 |
Trade Name | |
Synonyms | ARV110|ARV 110|Bavdegalutamide |
Drug Descriptions |
ARV-110 is bifunctional molecule that targets androgen receptor (AR) for proteolytic degradation resulting in reduced target gene expression, potentially leading to decreased tumor growth inhibition and apoptosis (Journal of Clinical Oncology 37, no. 7_suppl (March 1 2019) 259-259, PMID: 32503798). |
DrugClasses | Hormone - Anti-androgens 54 |
CAS Registry Number | NA |
NCIT ID | C160788 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Abiraterone + ARV-110 | ARV-110 Abiraterone | 0 | 1 |
ARV-110 | ARV-110 | 0 | 1 |