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Drug Name | REGN5678 |
Trade Name | |
Synonyms | REGN 5678|REGN-5678 |
Drug Descriptions |
REGN5678 is a bispecific antibody that targets prostate-specific membrane antigen (PSMA) and CD28, which may couple T-cells to PSMA-expressing tumor cells, potentially leading to enhanced T-lymphocyte activation and antitumor activity (J Clin Oncol 2021 39:6_suppl, TPS174). |
DrugClasses | PSMA Antibody 20 |
CAS Registry Number | NA |
NCIT ID | C162936 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cemiplimab + REGN5678 | Cemiplimab REGN5678 | 0 | 1 |
REGN5678 | REGN5678 | 0 | 1 |