REGN5678
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| Drug Name | REGN5678 |
| Trade Name | |
| Synonyms | REGN 5678|REGN-5678|nezastomig |
| Drug Descriptions |
REGN5678 is a bispecific antibody that targets prostate-specific membrane antigen (PSMA) and CD28, which may couple T-cells to PSMA-expressing tumor cells, potentially leading to enhanced T-lymphocyte activation and antitumor activity (J Clin Oncol 2021 39:6_suppl, TPS174). |
| DrugClasses | CD28 Antibody 12 PSMA Antibody 22 |
| CAS Registry Number | 2657613-60-8 |
| NCIT ID | C162936 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Cemiplimab + REGN5678 | Cemiplimab REGN5678 | 0 | 2 |
| REGN5678 | REGN5678 | 0 | 2 |
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