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Drug Name | SL-279252 |
Trade Name | |
Synonyms | SL 279252|SL279252|PD1-Fc-OX40L |
Drug Descriptions |
SL-279252 is a chimeric fusion protein that consists of the extracellular domains of PD-1 (PDCD1) and OX40L (TNFSF4) linked by an Fc domain, which may result in both immune checkpoint inhibition and TNF receptor activation, leading to increased antitumor immune response (PMID: 30563566). |
DrugClasses | Immune Checkpoint Inhibitor 149 |
CAS Registry Number | NA |
NCIT ID | C161803 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
SL-279252 | SL-279252 | 0 | 1 |